Heroin hepatitis

•  Of the first 27 patients who initiated CGT, 42% achieved a sustained viral response.
•  87% (13/15) of genotype-1 infected patients treated with direct acting antiviral agent achieved an undetectable viral load at 24weeks.

Concurrent group treatment for hepatitis C: Implementation and outcomes in a methadone maintenance treatment program.

J Subst Abuse Treat. 2012 Oct 2. pii: S0740-5472(12)00142-0. doi: 10.1016/j.jsat.2012.08.007. [Epub ahead of print]

Opioid itch

• μ-opioid receptor (MOR) isoform MOR1D is essential for morphine-induced scratching (MIS)

Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids.

Cell. 2011 Oct 14;147(2):447-58.