Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics.
J Clin Invest. 2012 Oct 1;122(10):3387-93. doi: 10.1172/JCI60390. Epub 2012 Oct 1.
2012年10月16日 星期二
Heroin gene postmortem
Method: We evaluated singlenucleotide polymorphisms of key genes within these systems in three populations of opiate abusers and controls, totaling 489 individuals from Europe and the United States with postmortem tissue.
Conclusion: Genetically influenced interactions between glutamatergic and dopaminergic pathways in opiate abusers
Dopamine receptor D1 and postsynaptic density gene variants associate with opiate abuse and striatal expression levels. Molecular Psychiatry (2012), 1–6
Conclusion: Genetically influenced interactions between glutamatergic and dopaminergic pathways in opiate abusers
Dopamine receptor D1 and postsynaptic density gene variants associate with opiate abuse and striatal expression levels. Molecular Psychiatry (2012), 1–6
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