2013年8月24日 星期六

methadone and buprrenorphine on dopamine receptors

Differential effects of methadone and buprenorphine on the response of D2/D3 dopamine receptors in adolescent mice.

Available online 9 August 2013, In Press 
  Methadone exposure disturbs the D2-like receptor's response, indicating a potential risk in administering methadone to adolescents. Buprenorphine appears to have a significantly lower effect on the behavioral sensitivity of D2/D3 dopamine receptors in adolescents.

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